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Buspirone
Clinical data
Pronunciation/ ヒ b juヒ s p ノェ r oハ n / ( BEW -spi-rohn )
Trade namesBuspar
AHFS/Drugs.comMonograph
MedlinePlusa688005
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationBy mouth (oral)
ATC codeN05BE01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : 邃-only UK: POM (Prescription only) US: 邃-only
Pharmacokinetic data
Bioavailability3.9% [4]
Protein binding86窶95% [5]
MetabolismHepatic (via CYP3A4) [2] [3]
Metabolites5-OH-Buspirone; 6-OH-Buspirone; 8-OH-Buspirone; 1-PP [6] [7] [8]
Elimination half-life2.5 hours [2]
ExcretionUrine: 29窶63% [5] Feces: 18窶38% [5]

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Galippe's experiments on this subject are very instructive and demonstrate the unfavorable action of blis- ters. Peter also observed a ease of broncho-pneu- monia in which this treatment caused erysipelas and gan- grene which resulted fatally. He men- tioned the case of another patient who buspar generic buspirone had been subjected to numerous applications of blisters, in whom albuminuria per- sisted for a year ; instill another ease albuminuria persisted tor two years and finally caused the patient's death.

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